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Using genomic DNA as common reference in microarray experiments has recently been tested by different laboratories (2, 3, 5, 7, 9, 20, 24-26). While some reported that experimental results of microarrays using genomic DNA reference conformed nicely to those obtained by cDNA: cDNA co-hybridization method, others acquired poor results. We hypothesized that these conflicting reports could be resolved...
The advance in high-throughput genomic technologies including microarrays has generated a tremendous amount of gene expression data for the entire genome. Deciphering transcriptional networks that convey information on members of gene clusters and cluster interactions is a crucial analysis task in the post-sequence era. Most of the existing analysis methods for large-scale genome-wide gene expression...
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