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This chapter provides overview of the Vagus nerve stimulation (VNS) Therapy device; describes the relevant neuroanatomy for VNS; explains possible mechanisms of action of VNS; analyzes published data on the safety, tolerability, and efficacy of VNS Therapy in patients with drug‐resistant epilepsy (DRE) and treatment‐resistant depression (TRD). Less direct evidence of the potential relevance of VNS...
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