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The current study describes both Aβ and tau abnormalities that accumulate in the brains of aged (16–21 years), but not young (<4 years) clinically characterized cats. Diffuse plaques that were morphologically different from what is typically observed in the human brain could be detected with 4G8 (Aβ17–24) or an Aβ1–42-specific antibody but not with N-terminal Aβ or an Aβ1–40-specific antibody....
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