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We describe a procedure for the production and peptide affinity purification of polyclonal antisera against synthetic peptides representing different domains of β-amyloid precursor protein (APP). Rabbits were immunised with keyhole limpet haemocyanin coupled to synthetic peptides representing the amino-terminal APP18-32, Kunitz-type protease inhibitor (KPI) region APP301-316, the A β region APP670-686,...
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