The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The beneficial effects of topical retinoids have been well recognised in different clinical conditions of acne, psoriasis and skin photodamage (Leyden et al, 1989). Skin irritation, however, is an unwanted side effect (Gilchrest, 1991) associated with topical retinoid treatment. Inhibition of the metabolism of endogenous retinoic acid (RA) is a novel approach to exploit the controlling action of...
Retinoic acid (RA) is a naturally occurring retinoid that is capable of fulfilling the epithelial differentiation and other systemic functions of Vit A in vivo. Inhibiting retinoic acid metabolism increases its biological potency, suggesting that retinoic acid acts directly and is not converted into an activated metabolite (Napoli and Race, 1987). In previous studies we have shown that cytochrome...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.