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We studied the association between plasma total homocysteine (tHcy), its determinants folate, vitamin B 12 , vitamin B 6 and MTHFR genotype, and bone mineral density (BMD) in 328 postmenopausal British women. When the subjects were assigned to one of 3 groups (control, osteopenic or osteoporotic) according to their BMD at the os calcis, those in the osteoporotic group had, compared...
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