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PurposeLong‐term survivors of Ewing sarcoma (EWS) are at considerable risk for future complications, including late relapse and death. Data on prognostic factors for late death in those who have survived beyond 5 years are lacking.
MethodsWe conducted a retrospective cohort study using the Surveillance, Epidemiology, and End Results database. We obtained clinical features and outcome data on 1,351...
BACKGROUND:The insulin‐like growth factor‐1 (IGF‐1) signaling pathway plays an important role in the pathology of Ewing sarcoma (ES). Retrospective studies have suggested that levels of IGF‐1 and IGF binding protein 3 (IGFBP‐3) are correlated with the outcome of patients with ES.
METHODS:The IGF‐1 signaling pathway was investigated prospectively in 269 patients who had localized, previously untreated...
BACKGROUND:Ewing sarcoma can arise in either bone or soft tissue. The purpose of this study was to investigate whether patient characteristics, treatment strategies, and outcomes differ between skeletal Ewing sarcoma and extraskeletal Ewing sarcoma (EES).
METHODS:Patients <40 years of age with Ewing sarcoma or peripheral primitive neuroectodermal tumor reported to the United States Surveillance,...
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