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QT interval-prolonging drug-drug interactions (QT-DDIs) may increase the risk of life-threatening arrhythmia. Despite guidelines for testing from regulatory agencies, these interactions are usually discovered after drugs are marketed and may go undiscovered for years.Using a combination of adverse event reports, electronic health records (EHR), and laboratory experiments, the goal of this study was...
A tracking algorithm operating in a dense target environment is described. This algorithm is designed for a passive optical (angle only) sensor handling a very large number of targets. For the application considered, the sensor has limited angular resolution and the sampling rate is exceedingly low. To further complicate the algorithm design issues, the underlying system is nearly unobservable. The...
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