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Background A single low dose (0.25 mg/kg) of primaquine is recommended as a gametocytocide in combination with artemisinin-based combination therapies for Plasmodium falciparum but its effect on post-treatment gametocyte circulation and infectiousness to mosquitoes has not been quantified. Methods In this randomised, double-blind, placebo-controlled trial, 360 asymptomatic parasitaemic children...
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