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Recent study observed defective autophagy in chondrocytes with Kashin–Beck Disease (KBD). To clarify the potential role of autophagy-related ATG4C gene in the development of KBD, we conducted an integrative analysis of genetic association, messenger ribonucleic acid (mRNA) and protein expression of ATG4C in KBD patients.1026 subjects (559 KBD patients and 467 healthy cases) were enrolled in discovery...
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