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Fatty acids and other components of the diet may modulate, among others, mechanisms involved in homeostasis, aging, and age-related diseases. Using a proteomic approach, we have studied how dietary oil affected plasma proteins in young (6 months) or old (24 months) rats fed lifelong with two experimental diets enriched in either sunflower or virgin olive oil. After the depletion of the most abundant...
Nuclear transcription factor κB (NF-κB) plays a key role in the inflammatory response and can be modulate by dietary fat. We have examined the effect of three diets, with different fat composition, on the activation of NF-κB on peripheral blood mononuclear cells (PBMCs).Sixteen healthy men followed three 4-week diets, in a randomised crossover design: a Western diet, rich in saturated fat (SFA) [22%...
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