The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Background
IL‐25 has been proposed to play a key role in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). This study aimed to evaluate the association of IL‐25 with the Th2‐biased inflammatory profiles in CRSwNP.
Methods
Nasal polyp (NP) tissues and control uncinate process tissues were collected from 92 patients with CRSwNP, 20 patients with chronic rhinosinusitis without...
Background
The generation of the tolerogenic dendritic cells (DC) is not fully understood yet. Forkhead box protein‐3 (Foxp3) is an important molecule in the immune tolerance. This study tests a hypothesis that DCs express Foxp3, which can be upregulated by Staphylococcal enterotoxin B (SEB).
Methods
The expression of Foxp3 by DCs was evaluated by real‐time RT‐PCR, Western blotting, flow cytometry,...
BackgroundHuman induced pluripotent stem cells (iPSCs) possess remarkable self‐renewal capacity and the potential to differentiate into novel cell types, such as mesenchymal stem cells (MSCs). iPSC‐MSCs have been shown to enhance tissue regeneration and attenuate tissue ischaemia; however, their contribution to the immune regulation of Th2‐skewed allergic rhinitis (AR) and asthma remains unclear....
Background:MicroRNAs (miRNAs) are known to regulate the inflammatory response in various cell types. However, the ability of miRNAs to modulate dendritic cells (DCs) function for allergen immunotherapy is unclear.
Objective:To assess the role of miR‐23b in the regulation of ovalbumin (OVA)‐induced DC differentiation and function and to investigate the related molecular mechanisms.
Methods:Bone marrow‐derived...
To cite this article: Zhang Y‐G, Li X‐B, Zhang J, Huang J, He C, Tian C, Deng Y, Wan H, Shrestha D, Yang Y‐Y, Fan H. The I/D polymorphism of angiotensin‐converting enzyme gene and asthma risk: a meta‐analysis. Allergy 2011; 66: 197–205.
AbstractBackground: The insertion/deletion (I/D) polymorphism of angiotensin‐converting enzyme (ACE) gene has been implicated in susceptibility to asthma, but a...
To cite this article: Xu G, Zhang L, Wang DY, Xu R, Liu Z, Han DM, Wang XD, Zuo KJ, Li HB. Opposing roles of IL‐17A and IL‐25 in the regulation of TSLP production in human nasal epithelial cells. Allergy 2010; 65: 581–589.
AbstractBackground: The importance of IL‐17A, IL‐17F, and IL‐25 in allergic rhinitis (AR), as well as their possible role in regulation on thymic stromal lymphopoietin (TSLP)...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.