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This paper enhances the hierarchical fuzzy model to deal with the classification problems by adopting evolutionary genetic algorithm (GA) with a modified artificial bee colony (ABC) algorithm. Traditionally, fuzzy classifier could not provide a sufficiently high classification rate in higher feature dimension with few rules. In the literature, the genetic algorithm can take advantage from the global...
In this paper, a novel computing methodology called DNA-RGA computing algorithm, which combines the characteristics of DNA and Real Coded Genetic algorithm, is proposed to design fuzzy controller and to improve the performance of systems. In order to explore the major merit of DNA-RGA computing algorithm in the field of control systems, this paper presents a variable PID-like fuzzy controller design...
The mechanics of many biological processes can only be uncovered through the analysis of spatio-temporal data. Kymographs are a popular tool for visualising dynamic processes whose movements can be mapped into a single dimension, such as mitosis, or cell division. However, global movements of a cell means the region of interest (ROI) used to create the kymograph must move with each frame. Here we...
Nitinol (TiNi) thin film is a potentially useful material for various clinical applications, e.g., vascular stents. In this study we examined the biological functions of bovine endothelial cell (BAEC) and bovine smooth muscle cells (BSMC) on 1-/spl mu/m thick amorphous TiNi films. BAEC and BSMC both attached on TiNi film, and exhibited increased cell spreading in the presence of serum containing media...
Transforming growth factor-/spl beta/1 (TGF-/spl beta/1) is believed to be a key player in wound healing, promoting cell proliferation, migration, and matrix synthesis in a variety of cell types. We have designed two peptides, i.e., cytomodulin-1 (CM-1) and cytomodulin-2 (CM-2), to simulate the binding domain of TGF-/spl beta/1. In this study we examined the bioactivity of the two synthetic peptides...
In an effort to develop small-diameter tissue-engineered vascular grafts (< 6 mm), collagen and fibrin gels seeded with human aortic smooth muscle cells (HASMCs) were constructed in a three-dimensional tubular environment and subjected to mechanical stimulation to investigate changes in cellular response and matrix remodeling. After testing various collagen and fibrin concentrations, experiments...
Hydrogel coatings have been widely researched as a nonfouling surface modification of materials for cardiovascular applications. In this study, we examined cell-surface interactions between a poly(acrylamide-copolyethylene glycol/acrylic acid) interpenetrating network (IPN) hydrogel and aortic endothelial cells (ECs). The IPN was covalently attached to polystyrene to form a nanometer scale thick hydrogel,...
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