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Aims/hypothesis. α-Endosulphine, a protein that belongs to the cAMP-regulated-phosphoprotein family, has been reported to modulate insulin secretion in vitro through interaction with the pancreatic beta-cell ATP-sensitive potassium (KATP) channel. In this study, we analysed the tissue distribution of α-endosulphine and determined its pancreatic cellular localization. Methods. Quantitative tissue...
Aims/hypothesis. α-Endosulphine, a protein that belongs to the cAMP-regulated-phosphoprotein family, has been reported to modulate insulin secretion in vitro through interaction with the pancreatic beta-cell ATP-sensitive potassium (KATP) channel. In this study, we analysed the tissue distribution of α-endosulphine and determined its pancreatic cellular localization. Methods. Quantitative tissue distribution...
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