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Specific high-affinity (K d = 3.4 nM) binding sites for 125 I-labelled angiotensin I (I 125 I]Ang I) were identified on an epithelial cell line (IEC-18) derived from the rat small intestine. The sites, which also have high affinity for Ang II, are insensitive to both AT 1 - and AT 2 -specific angiotensin receptor antagonists. The rank order...
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