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PurposeRetinal hypoxia plays a role in the pathophysiology of retinal vascular diseases such as diabetic retinopathy. Previous studies have shown that nitric oxide (NO) and cyclooxygenase (COX) products are involved in hypoxia‐induced dilatation of the retinal vessels. Therefore, the purpose of this study was to examine the effect of an NO donor and inhibition of COX products on the diameter regulation...
Purpose Retinal hypoxia with consequent changes in blood perfusion is a central feature in common vision threatening diseases. The aim of this study was to examine the effects of inhibiting COX and NO‐synthesis on hypoxia‐induced relaxation of retinal vessels in humans
Methods Twenty healthy persons aged 20‐55 years were examined on two days separated by 4‐7 days. The resting diameter and the diameter...
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