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Background and Objectives Several pathogen inactivation methods currently applied to therapeutic plasma may result in products with different hemostatic properties. This study aims at evaluating and comparing the hemostatic potential of different therapeutic plasma preparations currently available in France.
Materials and methods We studied three types of pathogen‐reduced plasma for transfusion...
Dans ce texte nous nous proposons d’expliquer succinctement la place de la thrombine dans l’hémostase et les caractéristiques pharmacologiques des anticoagulants inhibiteurs directs de la thrombine (IDT), les plus récents étant des petites molécules actives par voie orale. Du fait de la complexité des mécanismes de la coagulation, seules les études cliniques peuvent démontrer quelle molécule et quelles...
L'exploration hematologique a pour objectif la mise en evidence d'une pathologie hematologique bien definie et associee a un risque thrombotique (comme un syndrome myeloproliferatif), ou celle d'un ou plusieurs facteurs de risque thrombotique, qui peuvent etre genetiquement determines (comme une diminution de sensibilite a l'effet inhibiteur de la proteine C activee) ; cette mise en evidence est susceptible...
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