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Purpose:To investigate MRI biomarkers of muscle atrophy during cast immobilization of the lower leg.
Materials and Methods:Eighteen patients (8 male, 10 female), who had one lower leg immobilized in a cast, underwent 3.0 Tesla (T) MR imaging 5, 8, 15, 29, and 43 days after casting. Measurements were made on both lower legs of total muscle volume. Cross‐sectional area (CSA), fractional water content,...
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