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Butyrate, produced by colonic fermentation of dietary fibers is often hypothesized to beneficially affect colonic health. This study aims to assess the effects of butyrate on inflammation and oxidative stress in subjects with chronically mildly elevated parameters of inflammation and oxidative stress.Thirty-five patients with ulcerative colitis in clinical remission daily administered 60ml rectal...
Butyrate, a short-chain fatty acid produced by colonic microbial fermentation of undigested carbohydrates, has been implicated in the maintenance of colonic health. This study evaluates whether butyrate plays a role in oxidative stress in the healthy colonic mucosa.A randomized, double blind, cross-over study with 16 healthy volunteers was performed. Treatments consisted of daily rectal administration...
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