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Purpose: Several lines of evidence indicate that the complement system participates in the development of atherosclerotic lesion. In order to understand the roles of complement system in atherosclerosis, it is of great importance to study the site of synthesis of complement components and complement receptors. In this study, we investigated the C3 and complement receptor 1(CR1) expression of human...
Purpose: Paraoxonase (PONA) is associated with HDL and has been shown to prevent LDL oxidation in vitro. Genetic polymorphism of PONA and significant association of the B allele with coronary artery disease (CAD) were reported. In this study we determined the PONA genotype in the patients with cerebrovascular disease (CVD) and CAD in Japanese population.Methods: Study population was comprised of...
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