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The influence of decreased endogenous γ-aminobutyric acid (GABA) concentration on benzodiazepine receptor function was studied in the brain of living baboons. Positron emission tomography and the radiotracer [ 11 C]flumazenil combined with electroencephalography were used to determine the pharmacological properties of two benzodiazepine receptors agonists, diazepam and bretazenil, in...
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