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Aufgrund der Seltenheit des Peniskarzinoms in Mitteleuropa und Nordamerika stellen sich Betroffene oft erst in späten Tumorstadien vor. Die Diagnose kann meist als Blickdiagnose des Primärtumors gestellt werden. Klinisch sind dessen Morphologie, Größe und Lagebeziehungen sowie die inguinalen Lymphknoten von Interesse. Die Entfernung (mikro-)metastatisch befallener Lymphknoten ist prognostisch entscheidend...
Conventional renal cell carcinomas (CRCCs) were investigated for the expression of annexin II (ANX II) to determine out whether this calcium-binding protein could serve as a useful prognostic marker. CRCCs and adjacent nonneoplastic tissue from 33 patients were investigated for ANX II by immunohistochemistry, RT-PCR, and western blot analysis. ANX II expression was correlated with tumor differentiation...
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