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Periodic paralysis is a group of heterogeneous disorders caused by mutations of several ion channel genes including sodium, calcium and potassium channels. Andersen–Tawil syndrome (ATS) is a form of periodic paralysis, characterized by a triad of periodic muscle weakness, cardiac arrhythmia and dysmorphic features. KCNJ2 gene, which encodes Kir2.1 subunit and forms inward rectifying potassium channel...
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