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The insect pest Spodoptera litura is considered a major threat to many economically important food and commercial crops. The present study establishes the toxic effects of Sclerotium rolfsii lectin (SRL) against S. litura larvae fed an artificial diet containing the purified lectin. The toxicity of SRL, as determined by feeding assays using different concentrations of the lectin, showed marginal effects...
Cisplatin, a widely used anticancer drug, produces significant oto- and nephrotoxicity. Previous data from our laboratory, using cultured cell lines, indicated that cisplatin increases the expression of the adenosine A 1 receptor subtype through generation of reactive oxygen species and activation of nuclear factor-κB (NF-κB). Since the adenosine A 1 receptor plays an important role...
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