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Background
Data on HCV‐related hepatocellular carcinoma (HCC) early recurrence in patients whose HCC was previously cured, and subsequently treated by direct‐acting antivirals (DAAs), are equivocal.
Aim
To assess the risk of HCC early recurrence after DAAs exposure in a large prospective cohort of HCV‐cirrhotic patients with previous successfully treated HCC, also looking for risk factors for cancer...
Background and Aim: The pegylated interferon (PEG-IFN)/ribavirin combination has been shown to be effective for hepatitis C virus (HCV)-related compensated cirrhosis, but it frequently causes adverse events, leading to premature termination. In this open study we evaluated the safety and efficacy of early retreatment with leukocyte IFN-alpha in Child A HCV genotype 1b-infected cirrhotics intolerant...
In patients with respiratory failure, mechanical ventilation may further impair right ventricular (RV) function. To identify the best value of positive end-expiratory pressure (best PEEP) in individual patient, i.e. the one with the best arterial oxygen tension (PaO 2 ) and the smallest cardiac effects (decrease of RV stroke volume), 10 pts admitted to our intensive care unit with severe...
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