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An upconversion biocompatible implant is the first step of translating decades‐old near‐infrared nanotransducer research into wireless phototherapeutic devices that can be implanted underneath the skin. The use of a hydrogel and cladding results in an upconversion optical fiber that is able to upconvert in a flexible manner and even transmit NIR at maximal bending is described by Kah‐Leong Lim, Yong...
Near‐infrared (NIR) activatable upconversion nanoparticles (UCNPs) enable wireless‐based phototherapies by converting deep‐tissue‐penetrating NIR to visible light. UCNPs are therefore ideal as wireless transducers for photodynamic therapy (PDT) of deep‐sited tumors. However, the retention of unsequestered UCNPs in tissue with minimal options for removal limits their clinical translation. To address...
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