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Aim
CH1641 was discovered in 1970 as a scrapie isolate that was unlike all other classical strains of scrapie isolated so far. We performed bio‐assays of CH1641 in mice in order to further characterise this specific isolate.
Methods
We inoculated the original CH1641 isolate into ovine and bovine prion protein (PrP) transgenic mice as well as wild‐type mice. In addition, we performed cross‐ and...