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Melatonin (MLT) is a neurohormone known to be involved in the regulation of anxiety. Most of the physiological actions of MLT in the brain are mediated by two high-affinity G-protein-coupled receptors, denoted MT 1 and MT 2 . However, the particular role of these receptors in anxiety remains to be defined. Here we used a novel MT 2 -selective partial agonist, UCM765 to evaluate...
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