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The dose-related effects of estradiol 17-β at the doses 0.1 μg, 10 μg, 100 μg, 200 μg, 300 μg, 400 μg, 1000 μg/kg/day were determined on sperm motility, potency, fertility parameters, serum levels of LH, FSH, PRL and testosterone, weights of testes and accessory sex organs, weights of pituitary and adrenal glands. The drug was administered daily via sc route for a period of 60 days. Dose-related effects...
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