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Post-stent high pressure inflations (HPI) with aspirin and ticlopidine (AT) decrease subacute thrombosis and vascular complications (VC). To determine their influence on procedural and hospital costs, PTCA with stent placement for non-bailout indications (elective, suboptimal result post-balloon) in 663 patients (719 lesions) were reviewed: the initial 335 patients received coumadin (C) and no-HPI...
Few pharmacologic agents affect restenosis clinically. A recent large multi-center trial (TREAT) showed benefit (15% restenosis rate) of the anti-allergic and anti-keloid compound. To confirm this result and ascertain the possible mechanism we gave 100 mg/kg tranilast twice/d for 3 d before balloon angioplasty in the LAD and LCX, and stenting in the RCA in 18 pigs and continued until tissue harvest...
Background: The prognostic value of homocyst(e)ine (H(e)) levels in coronary artery disease (CAD) patients (pts) receiving PTCA or CABG was examined in the Emory Angioplasty vs. Surgery Trial (EAST).Methods: Of 392 multivessel disease pts who were randomized to an initial strategy of PTCA or CABG, 295 had at least one H(e) level measured during the first 3 yrs of the study. The mean H(e) level was...
It has been previously demonstrated that diabetics have worse outcomes after PTCA compared to non-diabetics. The purpose of this study was to investigate the clinical outcome in diabetic patients after Palmaz-Schatz (PS) stent implantation. Patients who underwent PS stent implantation between January 1, 1994 and December 31, 1996 were included in the study. Of 734 total patients, 179 (24.4%) were...
Elevations of creatinine kinase (CK) after angioplasty has been shown to have an adverse outcome. In this study we focused on the relation of the magnitude of CK elevation to survival. Patients who underwent angioplasty were divided into four groups: Group I (CK <250 mg/dl; n = 14034); Group II (CK 250-500 mg/dl; n = 6740), Group III (CK 500-750 mg/dl; n = 185); Group IV (CK >750 mg/dl). ...
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