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The schedule-dependent interaction of paclitaxel and doxorubicin was evaluated in four human cancer cell lines. The cells were exposed simultaneously or sequentially to the two agents for 24 h, and were then incubated in drug-free medium for 4 and 3 days, respectively. The cell growth inhibitions were determined by the MTT assay. The cytotoxic interactions at the ic 80 level were evaluated...
The catalyst is prepared from a Cu-loaded crystalline pentasil-type aluminosilicate precursor by extruding with 30-70 wt% of alkaline earth metal carbonates (especially CaCO 3 or SrCO 3 ), pelletizing, drying, and then calcining. The crystalline alumino-silicate precursor has a MFI-type microstructure and a SiO 22 O 3 mol ratio of 10:1.
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