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Dichlorvos (DDVP), an organophosphate pesticide, is reported to be genotoxic at high concentrations. However, the roles of DNA damage repair pathways in DDVP genotoxicity are not well characterized. To test whether pre- and post-replication pathways are involved, we measured changes in DNA migration (Comet assay) in the midgut cells of Drosophila melanogaster Oregon R+ larvae and in some mutants of...
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