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‘ARIMIDEX’ (A) is a new potent and highly selective aromatase inhibitor with a pharmacokinetic profile allowing once daily oral administration. Two randomised trials compared (A) to megestrol acetate (MA) as first-line or second-line treatment of PABC after relapse on prior adjuvant or advanced disease treatment Between 3/93 and 6/94, pts were randomised to (A) 1mg (263 pts), (A) 10mg (248 pts) or...
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