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Lipoprotein X (LpX) is an abnormal lipoprotein appears in lecithin:cholesterol acyltransferase (LCAT) deficiency characterized by abnormal lipid composition, low HDL cholesterol, corneal opacities and kidney disease. However, the reason why LpX appears, how it is catabolized, and the relationship with kidney disease are unknown. In this study we conducted in vivo kinetic study of LpX in LCAT deficiency...
Either active or passive smoking has been reported as a risk factor for coronary heart disease. Several studies showed decreased plasma ascorbic acid (AA) in smokers. We examined plasma AA levels and its redox status (ratio of dehydroascorbate (DHA) to total AA) in smokers and nonsmokers regularly exposed to environmental cigarette smoke (passive smokers). The study population consisted of 55 healthy...
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