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Obesity is generally associated with low‐grade inflammation. Adipose tissue macrophages (ATMs) orchestrate metabolic inflammation. The classical (M1‐like) or alternative (M2‐like) activation of ATMs is functionally coupled with the metabolic status of fat tissues. It has been found that T‐cell immunoglobulin‐ and mucin‐domain‐containing molecule‐4 (Tim‐4) inhibits inflammation by regulating macrophages...
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