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Inhibition of cytochrome P450 (CYP)‐mediated drug metabolism by dietary substances is the main cause of drug–food interactions in humans. The present study reports on the in vitro inhibition assays of human CYP3A4 genetically linked to the reductase domain of bacterial BM3 of Bacillus megaterium (BMR) resulting in the chimeric protein CYP3A4–BMR. The activity of this chimeric enzyme was initially...
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