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Zwei Arme zum Halten: Inspiriert von der Struktur basischer Leucin‐Zipper‐Proteine wurden hochaffine Peptide entworfen (Aptide), die neben einem stabilisierenden Gerüst (Tryptophan‐Zipper) zwei Regionen enthalten (orange und blau im Bild; AS=Aminosäure), die an das Zielprotein binden. Ein fluoreszenzmarkiertes Aptid, das an ein tumorspezifisches Protein bindet, wurde für Fluoreszenzbildgebung in vivo...
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