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Recently we demonstrated the inhibitory action on Growth Hormone (GH) secretion of an opioid heptapeptide, deltorphin (DT), that is highly selective in hinding δ-opioid receptors. To investigate the possible mechanism leading to the decrease in GH secretion by specific activation of δ-opioidergic pathway in man, we compared, in normal subjects, the effect of DT on GH secretion responses to two different...
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