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The effect of dopamine D 1 receptor blockade by SCH 23390 on the V–logI function of the ERG b- and d-waves was investigated in dark and light adapted frog eyes. We obtained that the blocker enhanced the amplitude of the b- and d-waves in both conditions of adaptation. The enhancing effect of the blocker was more pronounced on the rod- than cone-dominated responses for the both ERG waves. The...
The effect of blockade of voltage-gated sodium (Na v ) channels by tetrodotoxin (TTX) on the V-log I function of the ERG b- and d-waves was investigated in light and dark adapted frog eyecups. TTX diminished the b- and d-wave amplitude under both conditions of adaptation at all stimulus intensities except for the middle intensity range in dark adapted eyes, where it had no effect on the b-wave...
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