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Peroxynitrite is a highly reactive oxidant that has been implicated in a number of serious human diseases including cardiopathy, acute inflammation and cancer. The decomposition of peroxynitrite can be promoted efficiently by metalloporphyrins and are therefore important to detoxify the cytotoxic oxidant as therapeutic agents. A novel cobalt porphyrin was synthesized to investigate the scavenging...
Peroxynitrite is a potent oxidant in vivo which can result in serious diseases such as cardiopathy, acute inflammation and even cancer. Iron porphyrins have been shown to catalyze the efficient decomposition of peroxynitrite and are therefore important to detoxify the cytotoxic oxidant as therapeutic agents. A kinetic and theoretical study on peroxynitrite decomposition catalyzed by iron porphyrins...
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