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High-density imaging arrays have improved the image quality of diffuse optical tomography (HD-DOT) methods for mapping brain functions. Development of resting state measures of functional connectivity provides a brain assay logistically compatible with bedside imaging in the clinic. In this paper we review these advances and demonstrate the sensitivity of HD-DOT to acute ischemic stroke.
Key Points Noncontrast computed tomography (CT) is currently accepted as the gold standard for the detection of intracranial hemorrhage, though rigorous data is lacking (limited evidence) Magnetic resonance imaging (MRI) is equivalent to CT in the detection of intracranial hemorrhage (strong evidence), but its role in the evaluation of thrombolytic candidates has not been studied. Noncontrast CT of...
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