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Degeneration of motor neurons and their associated axons is a hallmark of amyotrophic lateral sclerosis, but reliable noninvasive lesion detection is lacking. In vivo diffusion tensor imaging was performed to evaluate neurodegeneration in the brainstem and cervical spinal cord of wild‐type and G93A‐SOD1 transgenic mice, an animal model of amyotrophic lateral sclerosis. A statistically significant...
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