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We investigated the involvement of Ca 2+ -independent activity of Ca 2+ /calmodulin-dependent protein kinase II (CaM kinase II) in stimulation of neurite outgrowth. When neuroblastoma Neruo2a (Nb2a) cells expressing the α isoform of CaM kinase II (Nb2a/α cells) were stimulated by plating, they changed shape from round to flattened, and began to form neurites within 15 min...
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