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Objective
The goal was to develop methods for detection of chromosomal and subchromosomal abnormalities in fetal cells in the mother's circulation at 10–16 weeks' gestation using analysis by array comparative genomic hybridization (CGH) and/or next‐generation sequencing (NGS).
Method
Nucleated cells from 30 mL of blood collected at 10–16 weeks' gestation were separated from red cells by density...
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