The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Die Mutation des axialen Liganden kann für die Feinjustierung der Carbenoidaktivität von Cytochrom P450 aus Bacillus megaterium genutzt werden. In der Zuschrift auf S. 6928 ff. stellen F. Arnold et al. die Entwicklung von Histidin‐ligiertem P450 vor, das die In‐vivo‐Cyclopropanierung mithilfe von Diazoverbindungen mit hoher Aktivität katalysiert. Mit diesem Enzym konnte eine Schlüsselvorstufe von...
Engineering enzymes capable of modes of activation unprecedented in nature will increase the range of industrially important molecules that can be synthesized through biocatalysis. However, low activity for a new function is often a limitation in adopting enzymes for preparative‐scale synthesis, reaction with demanding substrates, or when a natural substrate is also present. By mutating the proximal...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.