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An isocratic HPLC method with UV detection for simultaneous determination of four novel derivatives of daunorubicin and determination of selected derivatives in commonly used intravenous solvents was developed and validated. An RP-column and an acetonitrile-metha-nol-(2.88 g L-1sodium laurisulfate + 1.6 mL L-185% H3PO3), 9:1:10 mobile phase at a flow rate of 1.5 mL min-1were used. Detection wavelength...
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