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Community Cyber infrastructure for Advanced Marine Microbial Ecology Research and Analysis (CAMERA) is an eScience project to enable the microbial ecology community in managing the challenges of metagenomics analysis. CAMERA supports extensive metadata based data acquisition and access, as well as execution of metagenomics experiments through standard and customized scientific workflows. Users can...
Quantifying residue variability at each column in a multiple sequence alignment of amino acids helps in indicating their similarities, and is useful to highlight information about the significances of each position from the perspective of their structure, function, and evolution. It is becoming increasingly clear that the groups of amino acids that allow conserved replacement vary with the position...
Homology search is a fundamental tool in genomics and proteomics research and considerable attention has been paid to the development of faster homology finding algorithms. The most efficient homology search algorithms known are based on finding short exact or near exact subsequences and then extending these to form long matches. Traditional tools such as FASTA and BLAST use the consecutive seed model,...
The last decade has witnessed an exponential growth of sequence information in the field of biological macromolecules such as proteins and nucleic acids and their interactions with other molecules. Computational analyses for structure-function predictions based on such information are increasingly becoming an essential and integral part of modern biology. With rapid advances in the area, there is...
There has been little work in developing comprehensive research tools which would allow the researcher to study the complete interval and external structure of the cell as well as automatically classifying the cell structure. The authors describe an effort to combine these three functions into one computer-based imaging system. A description is given of the first part of this system, which is used...
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