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Recently, Scinto et al. reported that Alzheimer's disease (AD) patients exhibited a marked hypersensitivity in their pupil dilatation response to a cholinergic antagonist, tropicamide. Recent studies have also revealed the striking association between the apolipoprotein E 4 allele (ApoE4 allele) and sporadic and familial late-onset AD. These observations lead us to examine the association between...
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