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Leptin wird eine zentrale Rolle in der Knochenhomöostase zugeschrieben, sowohl durch systemische als auch durch lokale Wirkungen. Systemisch scheint Leptin die Knochenbildung zu inhibieren, kontrolliert durch eine Rückkopplungsschleife unter Beteiligung von Osteocalcin und Insulin. Auch wenn die Wirkung spezifisch für bestimmte Knochen sowie geschlechts- und zeitabhängig zu sein scheint, sind die...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.