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The K+‐Cl− cotransporter type 2 is the major Cl− extrusion mechanism in most adult neurons. This process in turn leads to Cl− influx upon activation of γ‐aminobutyric acid type A (GABAA) receptors and the canonical hyperpolarising inhibitory postsynaptic potential. Several neurological disorders are treated with drugs that target and enhance GABAA receptor signaling, including the commonly used benzodiazepine...
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